| | Protocol for Epidemiologic Study of the Health of Vietnam |
| | 7,81 | | MB | Veterans |
| | 257 | | stron |
| | 3750 | | ID | Centers for Disease Control and Prevention |
| | 2003 | | rok |
| | 1. Introduction 1 |
| | 2. Background 3 |
| | 2.1. Herbicide Usage in Vietnam 3 |
| | 2.2. Health Effects of Herbicides and Dioxin 4 |
| | 2.3. Diseases Affecting U.S. Troops in Vietnam 5 |
| | 2.4. Current Health of Vietnam Veterans 5 |
| | 2.5. Long-Term Health Status of Servicemen and Veterans 5 |
| | 3. Study Design Overview 6 |
| | 3.1. Agent Orange Study 6 |
| | 3.2. Vietnam Experience Study 8 |
| | 3.3. Selected Cancers Case-Control Study 8 |
| | 4. Study Procedures 10 |
| | 4.1. Selection of Study Subjects 10 |
| | 4.1.1. Agent Orange Study 10 |
| | 4.1.2. Vietnam Experience Study 15 |
| | 4.1.3. Selected Cancers Case-Control Study 16 |
| | 4.2. Location of Study Subjects 18 |
| | 4.3. Ascertainment of Health and Exposure Status 19 |
| | 4.3.1. Agent Orange and Vietnam Experience Studies 20 |
| | 4.3.1.1. Mortality Information 20 |
| | 4.3.1.2. Morbidity and Exposure Information 20 |
| | A. Health Interviews 21 |
| | —Sociodemographic Information 21 |
| | —Medical History 22 |
| | —Environmental and Occupational |
| | Exposure Information 22 |
| | —Military History 22 |
| | B. Medical and Psychological |
| | Examinations; Laboratory Tests 23 |
| | 4.3.2. Selected Cancers Case-Control Study 24 |
| | —Sociodemographic Information 25 |
| | —Family History of Cancer 25 |
| | —Medical History 25 |
| | —Environmental and Occupational |
| | Exposure Information 25 |
| | —Military History 25 |
| | 4.4. Sample Sizes, Statistical Power, and Participation Rates 26 |
| | 4.4.1. Agent Orange and Vietnam Experience Studies 26 |
| | 4.4.2. Selected Cancers Case-Control Study 28 |
| | 4.5. Pretests and Pilot Studies |
| | 4.5.1. Agent Orange and Vietnam Experience Studies |
| | 4.5.1.1. Military Records Pretests |
| | 4.5.1.2. Location Rate, Participation Rate, and Instrument Assessments |
| | 4.5.2. Selected Cancers Case-Control Study |
| | 4.6. Data Analysis and Quality Control |
| | 4.6.1. Timing of Analyses |
| | 4.6.2. Summary of Analytical Approach |
| | 4.6.3. Quality Control |
| | 5. Inferences from Possible Study Findings; Study Limitations |
| | 6. Report of Study Findings |
| | 7. Timetable, Milestones, and Reports |
| | 8. Investigators |
| | 9. Protocol Review; Study Oversight |
| | 10. Tables |
| | Appendices |
| | Cumulative Expected Numbers of Deaths by Cause in a Hypothetical Cohort of 6,000 Men Aged |
| | 22 in 1968 and Followed Through 1984 (17 Years) |
| | Power To Detect Various Relative Risks in the Agent Orange and Vietnam Experience Studies, by |
| | Prevalence of Condition in "Unexposed" Group Selected Health Outcomes Reported To Be |
| | Associated with Exposure to TCDD--Animal and Human Literature |
| | Estimated Prevalence of Vietnam Service and Expected Number of Cases of Cancer for the |
| | Selected Cancers Case-Control Study in Males Aged 30-54 in 1986 in the SEER Areas |
| | Power of Selected Cancers Case-Control Study To Detect Increased Relative Risks |
| | Protocol Outline (November 1982) |
| | Literature Review |
| | Topical List of Questionnaire Items for Agent Orange and Vietnam Experience Studies |
| | Topical List for Examination and Laboratory Testing for Agent Orange and Vietnam Experience |
| | Studies |
| | Topical List of Questionnaire Items for Selected Cancers Case-Control Study |
| | 12. References |
| | AGENT ORANGE STUDY PROTOCOL REVIEW |