| | The Use of Di-2-Ethylhexyl Phthalate in PVC Medical Devices: |
| | 0,29 | | MB | Exposure, Toxicity, and Alternatives |
| | 72 | | stron |
| | 4053 | | ID | Health Care Without Harm |
| | 2000 | | rok |
| | Table of Contents |
| | Executive Summary 1 |
| | Introduction 7 |
| | CHAPTER ONE |
| | Use of Polyvinyl Chloride Plastics and DEHP in Medical Devices 9 |
| | CHAPTER TWO |
| | Human Exposure to DEHP 11 |
| | CHAPTER THREE |
| | Toxicity of DEHP in Animals and Humans . 21 |
| | Disposition of DEHP 23 |
| | Acute toxicity 24 |
| | Reproductive and developmental toxicity . 24 |
| | Nephrotoxicity of DEHP . 28 |
| | Cardiotoxicity of DEHP 29 |
| | Pulmonary toxicity of DEHP 30 |
| | Hepatotoxicity of DEHP . 30 |
| | Mechanisms of effects of DEHP 33 |
| | Calculating human risk from DEHP exposure 37 |
| | CHAPTER FOUR |
| | Risk Management Options for DEHP in PVC Medical Devices . 39 |
| | CHAPTER FIVE |
| | Alternatives to PVC in the Medical Bags and Tubing Markets . 41 |
| | CHAPTER SIX |
| | Conclusions 53 |
| | Appendix: |
| | The Links Between PVC Production and Disposal and the Creation of Dioxin 55 |
| | Endnotes . 61 |
| | Bibliography 65 |