Report on Carcinogens, Eleventh Edition

45,3

MB

stron

4098

ID

U.S. Department of Health and Human Services

2002

rok

Table of Contents

I. Introduction

II. Carcinogens Listed in the Eleventh Report

A. Known to be Human Carcinogens

B. Reasonably Anticipated to be Human Carcinogens

III. Substance Profiles

Acetaldehyde

2-Acetylaminofluorene

Acrylamide

Acrylonitrile

Adriamycin® (Doxorubicin Hydrochloride)

Aflatoxins

Alcoholic Beverage Consumption

2-Aminoanthraquinone

o-Aminoazotoluene

4-Aminobiphenyl

1-Amino-2,4-dibromoanthraquinone

1-Amino-2-methylanthraquinone

Amitrole

o-Anisidine Hydrochloride

Arsenic Compounds, Inorganic

Asbestos

Azacitidine

Azathioprine

Benzene

Benzidine and Dyes Metabolized to Benzidine

Benzidine

Dyes Metabolized to Benzidine

Benzotrichloride

Beryllium and Beryllium Compounds

Bromodichloromethane

2,2-bis(Bromomethyl)-1,3-propanediol (Technical Grade)

1,3-Butadiene

1,4-Butanediol Dimethylsulfonate (Myleran®)

Butylated Hydroxyanisole (BHA)

Cadmium and Cadmium Compounds

Carbon Tetrachloride

Ceramic Fibers (Respirable Size)

Chlorambucil

Chloramphenicol

Chlorendic Acid

Chlorinated Paraffins (C12, 60% Chlorine)

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea

bis(Chloroethyl) Nitrosourea

Chloroform

bis(Chloromethyl) Ether and Technical-Grade Chloromethyl Methyl Ether

3-Chloro-2-methylpropene

4-Chloro-o-phenylenediamine

Chloroprene

p-Chloro-o-toluidine and p-Chloro-o-toluidine Hydrochloride

Chlorozotocin

Chromium Hexavalent Compounds

C.I. Basic Red 9 Monohydrochloride

Cisplatin

Coal Tars and Coal Tar Pitches

Cobalt Sulfate

Coke Oven Emissions

p-Cresidine

Cupferron

Cyclophosphamide

Cyclosporin A

Dacarbazine

Danthron (1,8-Dihydroxyanthraquinone)

2,4-Diaminoanisole Sulfate

2,4-Diaminotoluene

Diazoaminobenzene

1,2-Dibromo-3-chloropropane

1,2-Dibromoethane (Ethylene Dibromide)

2,3-Dibromo-1-propanol

tris(2,3-Dibromopropyl) Phosphate

1,4-Dichlorobenzene

3,3´-Dichlorobenzidine and 3,3´-Dichlorobenzidine Dihydrochloride

Dichlorodiphenyltrichloroethane (DDT)

1,2-Dichloroethane (Ethylene Dichloride)

Dichloromethane (Methylene Chloride)

1,3-Dichloropropene (Technical Grade)

Diepoxybutane

Diesel Exhaust Particulates

Diethyl Sulfate

Diethylstilbestrol

Diglycidyl Resorcinol Ether

3,3´-Dimethoxybenzidine and Dyes Metabolized to 3,3´-Dimethoxybenzidine

3,3´-Dimethoxybenzidine

Dyes Metabolized to 3,3´-Dimethoxybenzidine

4-Dimethylaminoazobenzene

3,3´-Dimethylbenzidine and Dyes Metabolized to 3,3´-Dimethylbenzidine

3,3´-Dimethylbenzidine

Dyes Metabolized to 3,3´-Dimethylbenzidine

Dimethylcarbamoyl Chloride

1,1-Dimethylhydrazine

Dimethyl Sulfate

Dimethylvinyl Chloride

1,4-Dioxane

Disperse Blue 1

Epichlorohydrin

Erionite

Estrogens, Steroidal

Ethylene Oxide

Ethylene Thiourea

di(2-Ethylhexyl) Phthalate

Ethyl Methanesulfonate

Formaldehyde (Gas)

Furan

Glass Wool (Respirable Size)

Glycidol

Hepatitis B

Hepatitis C

Heterocyclic Amines

2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MEIQ)

2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MEIQx)

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ)

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Hexachlorobenzene

Hexachloroethane

Hexamethylphosphoramide

Human Papillomaviruses: Some Genital-Mucosal Types

Hydrazine and Hydrazine Sulfate

Hydrazobenzene

Ionizing Radiation

X-Radiation and Gamma Radiation

Neutrons

Radon

Thorium Dioxide

Iron Dextran Complex

Isoprene

Kepone® (Chlordecone)

Lead and Lead Compounds

Lindane and Other Hexachlorocyclohexane Isomers

Melphalan

Methoxsalen with Ultraviolet A Therapy (PUVA)

2-Methylaziridine (Propylenimine)

4,4´-Methylenebis(2-chloroaniline)

4,4´-Methylenebis(N,N-dimethyl)benzenamine

4,4´-Methylenedianiline and its Dihydrochloride Salt

Methyleugenol

Methyl Methanesulfonate

N-Methyl-N´-nitro-N-nitrosoguanidine

Metronidazole

Michler's Ketone (4,4'-(Dimethylamino)benzophenone)

Mineral Oils (Untreated and Mildly Treated)

Mirex

Mustard Gas

Naphthalene

2-Naphthylamine

Nickel Compounds and Metallic Nickel