Systematic Review of Pesticide Human Health Effects

1,03
MB

188
stron

5181
ID Ontario College of Family Physicians

2004
rok

Table of Contents

Acknowledgements 1

Chapter 1 Introduction. 2

References. 5

Chapter 2 Methods 6

Chapter 3 Solid Tumours . 12

References. 17

Tables 22

Chapter 4 Non-Hodgkin’s Lymphoma. 36

References. 39

Tables 42

Chapter 5 Leukemia . 49

References. 52

Tables 55

Chapter 6 Genotoxicity 61

Immunotoxicity. 63

Genetic Susceptiblity to Pesticide Health Effects Mediated by Genetic Polymorphisms . 64

References. 66

Figure 1: N-weighted frequency of chromosome aberrations in exposed and non-exposed subjects

69

Tables 70

Chapter 7 Dermatologic Health Effects of Pesticides 79

References. 81

Tables 82

Chapter 8 Chronic Neurologic and Mental Health Effects. 86

References. 89

Tables 94

Chapter 9 Reproductive Outcomes Congenital Malformations . 111

Fecundability or Time to Pregnancy 112

Fertility . 113

Altered Growth 114

Fetal Death 114

Mixed Outcomes 116

References. 118

Tables 126

Chapter 10 Pesticide Health Effects and Children . 167

References. 169

Chapter 11 Implications for Family Doctors 172

References. 176

Appendix 1: Assessment Form for Review Papers 178

Appendix 2: Data Extraction Form .. 181