Mustard gas

0,17

MB

30

stron

5724

ID

Inchem

2005

rok

1. Name

1.1 Substance

1.2 Group

1.3 Synonyms

1.4 Identification numbers

1.4.1 CAS

1.4.2 Other numbers

1.5 Brand names/Trade names

1.6 Manufacturers, importers

2. SUMMARY

2.1 Main risks and target organs

2.2 Summary of clinical effects

2.3 Relevant laboratory analyses/sample collection

2.4 First-aid measures and management principles

3. PHYSICO-CHEMICAL PROPERTIES

3.1 Origin of the substance

3.2 Chemical structure (formula, molecular weight)

3.3 Physical properties

3.3.1 Colour

3.3.2 State/form

3.3.3 Description

3.4 Other characteristics

4. USES/HIGH RISK CIRCUMSTANCES OF POISONING

4.1 Uses

4.1.1 Uses

4.1.2 Description

4.2 High risk circumstances of poisoning

4.3 Occupationally exposed populations

5. ROUTES OF ENTRY

5.1 Oral

5.2 Inhalation

5.3 Dermal

5.4 Eye

5.5 Parenteral

5.6 Others

6. KINETICS

6.1 Absorption by route of exposure

6.2 Distribution by route of exposure

6.3 Biological half-life by route of exposure

6.4 Metabolism

6.5 Elimination and excretion by route of exposure

7. TOXICOLOGY

7.1 Mode of action

7.2 Range of toxicity

7.2.1 Human data

7.2.1.1 Adults

7.2.1.2 Children

7.2.2 Relevant animal data

7.2.3 Relevant in vitro data

7.2.4 Workplace standards

7.2.5 Acceptable daily intake (ADI) and other guideline levels

7.3 Carcinogenicity

7.4 Teratogenicity

7.5 Mutagenicity

7.6 Interactions

8. Toxicological analyses

9. CLINICAL EFFECTS

9.1 Acute poisoning

9.1.1 Ingestion

9.1.2 Inhalation

9.1.3 Skin exposure

9.1.4 Eye contact

9.1.5 Parenteral exposure

9.1.6 Other

9.2 Chronic poisoning

9.2.1 Ingestion

9.2.2 Inhalation

9.2.3 Skin exposure

9.2.4 Eye contact

9.2.5 Parenteral exposure

9.2.6 Other

9.3 Course, prognosis, cause of death

9.4 Systematic description of clinical effects

9.4.1 Cardiovascular

9.4.2 Respiratory

9.4.3 Neurological

9.4.3.1 CNS

9.4.3.2 Peripheral nervous system

9.4.3.3 Autonomic nervous system

9.4.3.4 Skeletal and smooth muscle

9.4.4 Gastrointestinal

9.4.5 Hepatic

9.4.6 Urinary

9.4.6.1 Renal

9.4.6.2 Other

9.4.7 Endocrine and reproductive systems

9.4.8 Dermatological

9.4.9 Eyes, ears, nose, throat: local effects

9.4.10 Haematological

9.4.11 Immunological

9.4.12 Metabolic

9.4.12.1 Acid-base disturbances

9.4.12.2 Fluid and electrolyte disturbances

9.4.12.3 Other

9.4.13 Allergic reactions

9.4.14 Other clinical effects

9.4.15 Special risks

9.5 Other

10. MANAGEMENT

10.1 General principles

10.2 Relevant laboratory analyses

10.2.1 Sample collection

10.2.2 Biomedical analysis

10.2.3 Toxicological analysis

10.3 Life support procedures and symptomatic/specific treatment

10.4 Decontamination

10.5 Elimination

10.6 Antidote treatment

10.6.1 Adults

10.6.2 Children

10.7 Management discussion

11. ILLUSTRATIVE CASES

11.1 Case reports from the literature

11.2 Internally-extracted data on cases

12. ADDITIONAL INFORMATION

12.1 Availability of antidotes